Aim high study nejm impact

Niacin in Patients with Low HDL Cholesterol ... - nejm.org

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Original Article from The New England Journal of Medicine — Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy ... Impact on Global Health Outcomes (AIM-HIGH ...

Niacin in Patients with Low HDL Cholesterol ... - nejm.org

Safety Profile of Extended-Release Niacin in the AIM-HIGH ...

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The results of the Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial were published in the Journal in …

Safety Profile of Extended-Release Niacin in the AIM-HIGH ...

New England Journal of Medicine | RG Journal Impact ...

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New England Journal of Medicine | Citations: 268,652 | One of the world's leading medical journals, the NEJM publishes original research and interpretive articles in major aspects of medicine: its ...

New England Journal of Medicine | RG Journal Impact ...

NIH stops clinical trial on combination cholesterol ...

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NIH stops clinical trial on combination cholesterol treatment. ... the earlier studies were not designed specifically to evaluate the impact of raising HDL on the risk of cardiovascular events while maintaining excellent LDL control. ... All AIM-HIGH study participants have been informed of the results and will be scheduled for clinic visits ...

NIH stops clinical trial on combination cholesterol ...

Population Health: The Ghost Aim - NEJM Catalyst

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12/14/2016 · The difficulty of defining the Ghost Aim makes it virtually impossible for health systems to know what their role and responsibility is to population health. Sometimes population health is described as something that occurs outside of health care delivery, such as a community’s rates of obesity, crime, or high school graduation.

Population Health: The Ghost Aim - NEJM Catalyst

Bill or No Bill, Health Care Leaders Still Have Work to Do ...

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10/18/2017 · If we could get the microphone more often, we’d talk about a fundamental pact many health care leaders like us have made to achieve the Triple Aim. The Triple Aim can be succinctly summarized as better health for populations, better care for patients, and lower costs of health care. It’s a simple yet powerful concept, and we use it as the ...

Bill or No Bill, Health Care Leaders Still Have Work to Do ...

The new england journal medicine - researchgate.net

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The AIM-HIGH Investigators* ... Impact on Global Health Out-comes (AIM-HIGH) trial are listed in ... The New England Journal of Medicine Downloaded from nejm.org on August 15, 2015. For personal ...

The new england journal medicine - researchgate.net

NHLBI Stops the AIM-HIGH Trial of Niacin - CardioExchange

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5/26/2011 · The AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health) trial of niacin has been stopped early by the NHLBI. The trial was designed to test the addition of high-dose, extended-release niacin to statins in people at risk for CV events who had well-controlled LDL but low HDL and elevated […]

NHLBI Stops the AIM-HIGH Trial of Niacin - CardioExchange

NEJM Knowledge+

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NEJM Knowledge+ combines gold-standard content with the most efficient, engaging and effective way to help you learn and prepare for your Board Exams.

NEJM Knowledge+

Safety Profile of Extended-Release Niacin in the AIM-HIGH ...

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7/17/2014 · TO THE EDITOR: The results of the Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial were published in the Journal in 2011. 1 This study showed no incremental clinical benefit from the addition of high-dose extended-release niacin (Niaspan, AbbVie) to statin therapy during a 36-month mean follow-up period …

Safety Profile of Extended-Release Niacin in the AIM-HIGH ...

AIM-HIGH: No Benefit for Niacin on Top of ... - CardioExchange

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The AIM-HIGH investigators aimed for the lofty target of proving the beneficial effects of niacin therapy. They did not succeed. Their findings were presented Tuesday morning at the AHA and published simultaneously in the New England Journal of Medicine. In AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes), 3414 […]

AIM-HIGH: No Benefit for Niacin on Top of ... - CardioExchange

Relations of GlycA and lipoprotein particle subspecies ...

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Relations of GlycA and lipoprotein particle subspecies with cardiovascular events and mortality: A post hoc analysis of the AIM-HIGH trial ... and W.E.B. to design and supervision of AIM-HIGH, study design, data analysis, and manuscript development. All authors have approved the final manuscript. ... impact on Global Health outcomes (AIM-HIGH ...

Relations of GlycA and lipoprotein particle subspecies ...

Health impact of E-cigarettes: a prospective 3.5-year ...

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11/17/2017 · Health impact of E-cigarettes: a prospective 3.5-year study of regular daily users who have never smoked ... This has never been formally tested in a research study. Thus, aim of the study was to ...

Health impact of E-cigarettes: a prospective 3.5-year ...

An analysis of radiological research publications in high ...

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Methods. A MEDLINE search was performed in five high impact general medical journals (AIM, BMJ, JAMA, Lancet, and NEJM) for all articles of which a radiologist was the first author between 1996 and 2010.The following information was abstracted from the original articles: radiological subspecialty, imaging technique used, type of research, sample size, study design, statistical analysis, study ...

An analysis of radiological research publications in high ...

“WHAT ABOUT AIM -HIGH?” WHERE DID WE GO WRONG--OR …

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“WHAT ABOUT AIM -HIGH?” “WHERE DID WE GO WRONG--OR DID WE?” AIM-HIGH: ATHEROTHROMBOSIS INTERVENTIONS IN METABOLIC SYNDROME WITHLOW HDL/HIGH TRIGLYCERIDES: IMPACT ON GLOBAL HEALTH OUTCOMES. Funded by NHLBI, Abbott Laboratories (Kos), Merck, Inc. U of W School of Medicine, NHLBI #5 U01 HL081616 ... of Study Findings

“WHAT ABOUT AIM -HIGH?” WHERE DID WE GO WRONG--OR …

Simplifying MOC for Family Physicians: The TRADEMaRQ Study ...

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March 30, 2015 Re “Simplifying MOC for Family Physicians: The TRADEMaRQ Study” 3/26/2015. [NEJM Knowledge+ ] If the ABFM really wants to simplify MOC the best way would be to compose a practical self-assessment series of booklets focusing on a single disease.

Simplifying MOC for Family Physicians: The TRADEMaRQ Study ...

Reporting quality of randomised controlled trial abstracts ...

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7/1/2016 · Objective The aim of this study was to assess adherence to the Consolidated Standards of Reporting Trials (CONSORT) for Abstracts by five high-impact general medical journals and to assess whether the quality of reporting was homogeneous across these journals. Design This is a descriptive, cross-sectional study. Setting Randomised controlled trial (RCT) abstracts in five high-impact general ...

Reporting quality of randomised controlled trial abstracts ...

New Evidence Fuels Concerns About The Safety Of Niacin

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7/16/2014 · The publication of the main results of the HPS2-THRIVE trial, along with new information from the AIM-HIGH trial, provide no evidence of a beneficial effect for niacin but do fuel concerns that it ...

New Evidence Fuels Concerns About The Safety Of Niacin

Conflicts of Interest at Medical Journals: The Influence ...

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10/26/2010 · For example, The New England Journal of Medicine ... But as our aim was to study the relative influence of industry-supported trials on the impact factor, this discrepancy is likely not so important, as errors in citing studies would be expected to be unrelated to the type of support they received. ... we find that the 2007 impact factor of ...

Conflicts of Interest at Medical Journals: The Influence ...

Reporting data analysis methods in high-„impact ...

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The New England Journal of Medicine (NEJM) and the Lancet are two of the most eminent medical ... Our aim in this study was to evaluate the application and complexity of data analytical methods in high-impact respiratory journals, and to compare the statistical methods and reporting in these respiratory ...

Reporting data analysis methods in high-„impact ...

The health economic impact of disease management programs ...

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7/3/2013 · There is insufficient evidence of the cost-effectiveness of Chronic Obstructive Pulmonary Disease (COPD) Disease Management (COPD-DM) programs. The aim of this review is to evaluate the economic impact of COPD-DM programs and investigate the relation between the impact on healthcare costs and health outcomes. We also investigated the impact of patient-, intervention, and study …

The health economic impact of disease management programs ...

Open Access Research Reporting quality of randomised ...

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high-impact general medical journals: a review and analysis ... Objective: The aim of this study was to assess adherence to the Consolidated Standards of Reporting Trials (CONSORT) for Abstracts by five high-impact ... 2011 and 2014 in The New England Journal of Medicine (NEJM), the Annals of Internal Medicine (Annals IM), The

Open Access Research Reporting quality of randomised ...

Conflicts of Interest at Medical Journals: The Influence ...

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Methods and Findings. We sampled six major medical journals (Annals of Internal Medicine, Archives of Internal Medicine, BMJ, JAMA, The Lancet, and New England Journal of Medicine [NEJM]).For each journal, we identified randomised trials published in 1996–1997 and 2005–2006 using PubMed, and categorized the type of financial support.

Conflicts of Interest at Medical Journals: The Influence ...

The new england journal medicine - mfprac.com

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in High-Risk Patients The HPS2-THRIVE Collaborative Group* ABSTRACT ... Heart Protection Study 2–Treatment of HDL to Reduce the Incidence of Vascu-lar Events (HPS2-THRIVE) is provided ... The New England Journal of Medicine Downloaded from nejm.org by KEVIN ROSTEING on August 29, 2014. For personal use only.

The new england journal medicine - mfprac.com

How much does it cost to publish a review paper in an ...

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9/6/2015 · How much does it cost to publish a review paper in an international journal? Update Cancel. a d b y U T A r l i n g t o n. Nurses, earn your RN to BSN degree for only $8,995. Graduate from the University of Texas at Arlington online in as few as 9 months. ... But of course for high impact journals like Nature, NEJM, Lancet- it is difficult to ...

How much does it cost to publish a review paper in an ...

Cholesterol and Controversy: Past, present and Future ...

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11/15/2011 · It was becoming clearer that diet had an impact on cholesterol levels, and therefore, the incidence of heart attacks. ... Conclusions from the AIM-HIGH study suggest ... In a perspective article ...

Cholesterol and Controversy: Past, present and Future ...

SATURN and AIM-HIGH: ‘Back down to planet Earth’

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The Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin (SATURN) is a prospective, randomized, multicenter, SATURN and AIM-HIGH: ‘Back down to ...

SATURN and AIM-HIGH: ‘Back down to planet Earth’

Most recent papers with the keyword Review and nejm | Read ...

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Read papers from the keyword Review and nejm with Read by QxMD. ... Review of : The Dry Eye Assessment and Management Study Research Group. N-3 fatty acid supplementation for the treatment of dry eye disease. NEJM 2018;378:1681-90. 30470708. December 2018: Drug and Therapeutics Bulletin.

Most recent papers with the keyword Review and nejm | Read ...

NEJM | MedicalResearch.com | Page 6

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In considering best approaches, we noted that there was an absence of prior research in which the sickle cell trait status of an entire, large, physically-active study population was known. This limitation could introduce bias to inflate the apparent impact of a theorized predictive factor.

NEJM | MedicalResearch.com | Page 6

AIM-HIGH trial | Drug Truths

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A recent study reported in The New England Journal of Medicine (NEJM.org, 11/15/11), along with an accompanying editorial, call into question the value of using niacin to treat CV disease. The AIM-HIGH trial, co-sponsored by the NIH and Abbott, looked at patients with established CV disease who were already on intensive statin therapy.

AIM-HIGH trial | Drug Truths

VASCEPA® (icosapent ethyl) | REDUCE-IT™: A landmark CV ...

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One study showed no impact on CV events in patients hospitalized for acute coronary syndrome [O’Donoghue et al., JAMA 2014]. The other study showed no impact on CV events in patients with chronic coronary disease (prior myocardial infarction, prior revascularization, or multivessel coronary disease) [STABILITY Investigators, NEJM 2014].

VASCEPA® (icosapent ethyl) | REDUCE-IT™: A landmark CV ...

Reporting data analysis methods in high-impact respiratory ...

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4/1/2018 · Data analysis methods play an important role in respiratory research. We evaluated the application and complexity of data analytical methods in high-impact respiratory journals and compared the statistical reporting in these respiratory articles with reports published in other eminent medical journals. This study involved a total of 160 papers published in 2015 in the European Respiratory ...

Reporting data analysis methods in high-impact respiratory ...

COMPare: a prospective cohort study correcting and ...

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Methods. We identified five high-impact journals endorsing Consolidated Standards of Reporting Trials (CONSORT) (New England Journal of Medicine, The Lancet, Journal of the American Medical Association, British Medical Journal, and Annals of Internal Medicine) and assessed all trials over a six-week period to identify every correctly and incorrectly reported outcome, comparing published ...

COMPare: a prospective cohort study correcting and ...

Niacin Does Not Reduce Heart Attack, Stroke Risk in Stable ...

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At an 8 a.m. EST press conference today at the American Heart Association meeting, UB professor of medicine William E. Boden, MD, discusses the AIM-HIGH clinical trial, which found that niacin provides no incremental benefit to patients with atherosclerotic heart disease, whose levels of LDL cholesterol and non-HDL (which contributes to plaque in the arteries) were very well-controlled.

Niacin Does Not Reduce Heart Attack, Stroke Risk in Stable ...

Cardiovascular Disease and Diabetes – Management of ...

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Prevalence Diabetes – A Cardiovascular Disease • Framingham Heart Study – Diabetes increased risk for CHD 2 times in men and 3 times in women. • MRFIT study – 12 year risk for cardiovascular death 9.7% for diabetes versus 2.6% without diabetes • Emerging Risk Factors Collaboration – Meta-analysis of 102 studies with over 500,000 subjects.

Cardiovascular Disease and Diabetes – Management of ...

Clinical Case Reports - Wiley Online Library

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WANTED! Clinical Case Reports is seeking a Senior Editor for our newly-formed Social Care specialty area.. Social care is defined as the provision of social work, personal care, protection or social support services to children or adults in need or at risk, or adults with …

Clinical Case Reports - Wiley Online Library

Niacin's Triple Paradox and Thoughts on HDL - Lipid

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9/20/2013 · AIM-HIGH Trial AIM-HIGH compared combined therapy with statin + extended-release niacin (ERN) vs. intensive statin therapy alone in 3,414 patients with established CV disease and low baseline HDL-C. Primary endpoint was a composite of time to first event for coronary death, MI, ischemic stroke, hospitalized ACS, or symptom-driven revascularization.

Niacin's Triple Paradox and Thoughts on HDL - Lipid
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